Description

1-Bromo-4-(Ethylsulfonyl)-2-Fluorobenzene is a high-purity fluorinated and sulfonated aromatic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring bromine, fluorine, and an ethylsulfonyl group, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in sulfonamide-based drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine and sulfone groups enhance biological activity.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and functional handles.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations.
• Chemical Library Development: Employed in medicinal chemistry for parallel synthesis and the creation of diverse compound libraries for high-throughput screening.

Basic Information

Product Name	1-Bromo-4-(Ethylsulfonyl)-2-Fluorobenzene
CAS No.	779329-61-2
Molecular Formula	C8H8BrFO2S
Molecular Weight	267.12 g/mol
Synonyms	1-Bromo-4-(ethylsulfonyl)-2-fluorobenzene; 2-Fluoro-1-bromo-4-(ethylsulfonyl)benzene; 4-Bromo-3-fluoroethylsulfonylbenzene; Benzene, 1-bromo-4-(ethylsulfonyl)-2-fluoro-; Ethyl 4-bromo-3-fluorophenyl sulfone
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(Ethylsulfonyl)-2-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications in cGMP environments and research requiring the highest material integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.