Description

(R)-2-Amino-1,1,1-Trifluoropropane CAS NO 779303-24-1 is a high-value, chiral fluorinated building block essential for modern synthetic chemistry. Its unique trifluoromethyl group and stereogenic center make it a critical intermediate for introducing fluorine atoms and specific three-dimensional configurations into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of fluorinated active pharmaceutical ingredients (APIs), particularly in protease inhibitors and CNS-targeting drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty fluorinated polymers and advanced organic electronic materials.
• Peptide Mimetics: Incorporated into peptide backbones to create analogs with improved bioavailability and resistance to enzymatic degradation.

Basic Information

Product Name	(R)-2-Amino-1,1,1-Trifluoropropane
CAS No.	779303-24-1
Molecular Formula	C3H6F3N
Molecular Weight	113.08 g/mol
Synonyms	(R)-1,1,1-Trifluoro-2-propanamine; (R)-2-Amino-1,1,1-trifluoropropane; (R)-1,1,1-Trifluoroisopropylamine; (R)-α-Trifluoromethyl ethylamine; (R)-TFPA; (R)-Trifluoroalanine methylene homolog; (R)-2-Aminopropyl trifluoride
EINECS	Contact for details

Quality Control

Every batch of our (R)-2-Amino-1,1,1-Trifluoropropane is produced under strict quality management protocols. We guarantee high chiral purity and chemical consistency to meet the stringent requirements of process chemistry and advanced research. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing chiral purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.