Description

3,4-Dihydrocinnamic Acid (L-Alanine Methyl Ester) Amide is a specialized chiral building block and pharmaceutical intermediate. This compound is valued for its role in the synthesis of more complex molecules, particularly in medicinal chemistry and peptide research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to incorporate specific chiral motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and metabolic targets.
• Peptidomimetics Research: Serves as a constrained dipeptide analog for designing novel peptide-like molecules with enhanced stability and bioavailability.
• Chemical Biology Probes: Used in the synthesis of labeled compounds and molecular probes for studying enzyme mechanisms and protein interactions.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective synthesis to introduce defined stereocenters.
• Academic & Institutional R&D: A valuable reagent for universities and research institutes conducting studies in organic synthesis and medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: A requested building block for custom synthesis projects at CDMOs (Contract Development and Manufacturing Organizations).

Basic Information

Product Name	3,4-Dihydrocinnamic Acid (L-Alanine Methyl Ester) Amide
CAS No.	778624-05-8
Molecular Formula	C13H18N2O3
Molecular Weight	250.29 g/mol
Synonyms	L-Alanine, N-(3-phenylpropanoyl)-, methyl ester; (S)-Methyl 2-(3-phenylpropanamido)propanoate; Methyl (S)-2-(3-phenylpropanamido)propanoate; 3-Phenyl-N-[(1S)-1-(methoxycarbonyl)ethyl]propanamide; L-Alanine methyl ester amide of 3,4-dihydrocinnamic acid; Dihydrocinnamoyl-L-alanine methyl ester
EINECS	Contact for details

Quality Control

Our 3,4-Dihydrocinnamic Acid (L-Alanine Methyl Ester) Amide is produced under a strict quality management system. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Optical Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.