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n-Methyl (R)-1-Ferrocenyl-(S)-(2-Diphenylphosphino)Ethylamine CAS NO 778511-13-0


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CAS No.:778511-13-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-Methyl (R)-1-Ferrocenyl-(S)-(2-Diphenylphosphino)Ethylamine is a chiral ferrocenyl phosphine ligand, a sophisticated organometallic compound designed for asymmetric synthesis. Its value lies in its ability to induce high enantioselectivity in catalytic transformations, which is critical for producing single-enantiomer intermediates in pharmaceutical and fine chemical manufacturing. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity chiral auxiliaries to develop efficient synthetic routes.

Application

  • As a chiral ligand in asymmetric hydrogenation reactions for the synthesis of enantiomerically pure amino acids and pharmaceutical intermediates.
  • Catalyst component in asymmetric carbon-carbon bond-forming reactions, such as allylic alkylation.
  • Key reagent in the development of novel catalytic systems for academic and industrial research in organometallic chemistry.
  • Used in the synthesis of complex natural products and active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
  • Precursor for the preparation of other modified ferrocenyl phosphine ligands with tailored steric and electronic properties.

Basic Information

Product Name n-Methyl (R)-1-Ferrocenyl-(S)-(2-Diphenylphosphino)Ethylamine
CAS No. 778511-13-0
Molecular Formula C26H28FeNP
Molecular Weight 441.33 g/mol
Synonyms (R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethylmethylamine; (R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethylmethylamine; Josiphos SL-J009-1; (R)-1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyl-N-methylamine; (R)-[1-[(S)-2-(Diphenylphosphino)ferrocenyl]ethyl]methylamine; n-Methyl-(R)-1-ferrocenylethyl-(S)-2-diphenylphosphineamine; Chiral Ferrocenyl Phosphine Ligand
EINECS Contact for details

Quality Control

Our n-Methyl (R)-1-Ferrocenyl-(S)-(2-Diphenylphosphino)Ethylamine is produced under strict quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and identity is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item Specification
Appearance Orange to red crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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