Description

Cyclobutanecarboxamide, 1-Amino-2-Methyl-, (1S,2R)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its unique cyclobutane scaffold and functional groups make it a valuable intermediate for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, antiviral agents, and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where the rigid cyclobutane structure can impart favorable biological activity and metabolic stability.
• Advanced Material Research: Serves as a precursor for specialty polymers, liquid crystals, or ligands for asymmetric catalysis, leveraging its defined stereochemistry.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of fine chemicals and active pharmaceutical ingredients (APIs).
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting studies in synthetic methodology and stereoselective transformations.

Basic Information

Product Name	Cyclobutanecarboxamide, 1-Amino-2-Methyl-, (1S,2R)- (9Ci)
CAS No.	777850-52-9
Molecular Formula	C6H12N2O
Molecular Weight	128.17 g/mol
Synonyms	(1S,2R)-1-Amino-2-methylcyclobutanecarboxamide; (1S,2R)-2-Methyl-1-aminocyclobutanecarboxamide; 1-Amino-2-methylcyclobutanecarboxamide (1S,2R)-; 777850-52-9; (1S,2R)-1-Amino-2-methyl-1-cyclobutanecarboxamide
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxamide, 1-Amino-2-Methyl-, (1S,2R)- (9Ci) is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for research and process development. A Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.