Description

Glycine, N-(2,2,2-Trifluoroethyl)- (9Ci) is a specialized fluorinated derivative of the amino acid glycine, distinguished by the presence of a trifluoroethyl group. This structural modification imparts unique physicochemical properties, making it a valuable building block in advanced chemical synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors. The compound, identified by CAS number 774527-31-0, serves as a critical intermediate for creating novel molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Research: Used in the synthesis of novel herbicides and pesticides, where the fluorine atoms can improve lipophilicity and environmental persistence.
• Peptide Mimetics: Serves as a non-natural amino acid analog in the design of peptide-based therapeutics and diagnostic agents.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create chelating ligands for catalysis and material science applications.
• Fluorine Chemistry Research: A fundamental reagent for studying the effects of fluorine substitution on molecular conformation and reactivity in academic and industrial R&D.
• Chemical Biology Probes: Useful for incorporating fluorine tags into biomolecules for studies using techniques like 19F NMR spectroscopy.

Basic Information

Product Name	Glycine, N-(2,2,2-Trifluoroethyl)- (9Ci)
CAS No.	774527-31-0
Molecular Formula	C4H6F3NO2
Molecular Weight	157.09 g/mol
Synonyms	2,2,2-Trifluoroethylglycine; N-(2,2,2-Trifluoroethyl)glycine; (2,2,2-Trifluoroethyl)aminoacetic Acid; Glycine, N-(trifluoroethyl)-; 2-[(2,2,2-Trifluoroethyl)amino]acetic Acid; Aminoacetic acid, N-(2,2,2-trifluoroethyl)-; F3C-CH2-NH-CH2-COOH
EINECS	Contact for details

Quality Control

Our Glycine, N-(2,2,2-Trifluoroethyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.