Description

2-Propanone, 1,1,3,3,3-Pentafluoro-1-Hydroxy- (9Ci) is a specialized fluorinated hydroxy ketone derivative, offering a unique combination of a reactive carbonyl group and a fluorinated alcohol moiety. This compound is valued for its role as a versatile fluorinated building block in advanced synthetic chemistry, enabling the introduction of fluorine atoms to enhance the properties of target molecules. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel compounds with improved metabolic stability, lipophilicity, and bioavailability.

Application

• Pharmaceutical Intermediate: A key fluorinated synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting enhanced drug-like properties.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and pesticides where the introduction of fluorine atoms can increase biological activity and environmental stability.
• Advanced Material Precursor: Serves as a building block for specialty polymers, liquid crystals, and fluorinated surfactants with unique surface properties and chemical resistance.
• Organic Synthesis & Catalysis: Employed in academic and industrial R&D for constructing complex organic molecules, often as a reagent in nucleophilic addition or condensation reactions.
• Fluorine Chemistry Research: A valuable compound for studying structure-activity relationships (SAR) and the effects of specific fluorine substitution patterns in molecular design.

Basic Information

Product Name	2-Propanone, 1,1,3,3,3-Pentafluoro-1-Hydroxy- (9Ci)
CAS No.	773812-22-9
Molecular Formula	C3H3F5O2
Molecular Weight	166.05 g/mol
Synonyms	1-Hydroxy-1,1,3,3,3-pentafluoro-2-propanone; 1,1,3,3,3-Pentafluoro-1-hydroxy-2-propanone; 1,1,3,3,3-Pentafluoro-2-hydroxy-2-propanone; Pentafluoroacetone hydrate (keto form); 2-Propanone, 1-hydroxy-1,1,3,3,3-pentafluoro-; α-Hydroxy-α,α,β,β,β-pentafluoroacetone; TFAA hydrate analog
EINECS	Contact for details

Quality Control

Our 2-Propanone, 1,1,3,3,3-Pentafluoro-1-Hydroxy- (9Ci) is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, assay, and impurity profiles are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its highly volatile nature, keep containers tightly sealed when not in use and away from heat sources and open flame. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.