Description

2-(2-Bromo-5-Fluorophenyl)-1,3-Dioxolane is a high-purity fluorinated and brominated aromatic building block, specifically a protected aldehyde derivative, essential for advanced organic synthesis. Its core value lies in enabling precise molecular construction, particularly in the development of complex, biologically active molecules where regioselectivity and functional group compatibility are critical. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in kinase inhibitors, CNS-active compounds, and anti-cancer agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides that leverage the unique properties of fluorine and bromine atoms.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized phosphine or nitrogen-based ligands used in asymmetric catalysis.
• Material Science: Employed in the synthesis of fluorinated liquid crystals, organic semiconductors, and polymers with tailored electronic properties.
• Chemical Biology: Acts as a probe or linker molecule in bioconjugation and the development of chemical tools for biological studies.
• Custom Synthesis & Scale-up: A critical starting material for contract research and manufacturing organizations (CROs/CMOs) engaged in custom synthesis projects.

Basic Information

Product Name	2-(2-Bromo-5-Fluorophenyl)-1,3-Dioxolane
CAS No.	773094-69-2
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	2-(2-Bromo-5-fluorophenyl)-1,3-dioxolane; 1,3-Dioxolane, 2-(2-bromo-5-fluorophenyl)-; 2-Bromo-5-fluorobenzaldehyde ethylene acetal; 2-Bromo-5-fluorobenzaldehyde 1,3-dioxolane; (2-Bromo-5-fluorophenyl)-1,3-dioxolane; 5-Fluoro-2-bromobenzaldehyde ethylene acetal; Benzaldehyde, 2-bromo-5-fluoro-, cyclic ethylene acetal
EINECS	Contact for details

Quality Control

Our 2-(2-Bromo-5-Fluorophenyl)-1,3-Dioxolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Every lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for fine chemicals, and our quality protocols are designed to meet the stringent requirements of research and development as well as scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥96.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.