Description

4-Fluoro-2-Methylbenzylamine is a versatile fluorinated aromatic amine building block, essential for the synthesis of complex organic molecules. Its value lies in the strategic introduction of both a reactive primary amine and a fluorine substituent, which can dramatically alter the biological activity and physicochemical properties of target compounds. This high-purity intermediate is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Functional Material Production: Employed in the synthesis of advanced polymers, liquid crystals, and electronic materials that require fluorinated aromatic components.
• Chemical Research & Development: A valuable building block in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring fluorinated benzylamine derivatives.

Basic Information

Product Name	4-Fluoro-2-Methylbenzylamine
CAS No.	771574-00-6
Molecular Formula	C8H10FN
Molecular Weight	139.17 g/mol
Synonyms	(4-Fluoro-2-methylphenyl)methanamine; 2-Methyl-4-fluorobenzylamine; 4-Fluoro-2-methylbenzenemethanamine; α-Amino-4-fluoro-2-methyltoluene; 4-Fluoro-o-tolylmethylamine; 1-(4-Fluoro-2-methylphenyl)methanamine; 4-Fluoro-2-methyl-benzylamine; Benzenemethanamine, 4-fluoro-2-methyl-
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methylbenzylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.