Description

n-[4-[(4-Amino-2-Fluorophenyl)Thio]Phenyl]Acetamide is a high-purity, specialized organic intermediate featuring a unique thioether-linked aromatic structure with amino and acetamide functional groups. This compound is valued for its role as a critical building block in advanced pharmaceutical synthesis and materials science research. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Serves as a building block for developing new herbicides and fungicides, leveraging its fluorinated aromatic core.
• Material Science: Used in the research and development of advanced polymers and liquid crystals, where its rigid, functionalized structure can impart specific properties.
• Organic Synthesis: Employed in academic and industrial laboratories for constructing complex heterocyclic compounds and for Suzuki-Miyaura or Buchwald-Hartwig cross-coupling reactions.
• Dye & Pigment Intermediate: Acts as a precursor in the synthesis of specialized dyes and pigments due to its amino and thioether groups.

Basic Information

Product Name	n-[4-[(4-Amino-2-Fluorophenyl)Thio]Phenyl]Acetamide
CAS No.	771477-12-4
Molecular Formula	C14H13FN2OS
Molecular Weight	276.33 g/mol
Synonyms	N-[4-[(4-Amino-2-fluorophenyl)sulfanyl]phenyl]acetamide; 4'-Acetamido-4-amino-2-fluorodiphenyl sulfide; 2-Fluoro-4-[(4-acetamidophenyl)thio]aniline; Acetamide, N-[4-[(4-amino-2-fluorophenyl)thio]phenyl]-; 771477-12-4; 4-Acetamidophenyl 4-amino-2-fluorophenyl sulfide
EINECS	Contact for details

Quality Control

Our n-[4-[(4-Amino-2-Fluorophenyl)Thio]Phenyl]Acetamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.