Description

3-Bromo-5-Hydroxybenzonitrile is a versatile halogenated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and a hydroxy group ortho to the nitrile, makes it a valuable precursor for constructing complex heterocyclic systems and functionalized aromatic compounds. This intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in the synthesis of kinase inhibitors, receptor modulators, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and material science.
• Functional Material Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers.
• Custom Chemical Synthesis: A versatile starting material for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds.

Basic Information

Product Name	3-Bromo-5-Hydroxybenzonitrile
CAS No.	770718-92-8
Molecular Formula	C7H4BrNO
Molecular Weight	198.02 g/mol
Synonyms	5-Bromo-3-cyanophenol; 3-Cyano-5-bromophenol; 5-Hydroxy-3-bromobenzonitrile; Benzonitrile, 3-bromo-5-hydroxy-; 3-Bromo-5-hydroxybenzenecarbonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Hydroxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.