Description

L-Aspartic Acid, 3-Fluoro-, 4-Methyl Ester (9Ci) is a fluorinated derivative of the amino acid aspartic acid, specifically engineered as a protected ester. This compound serves as a critical chiral building block and synthetic intermediate in advanced organic synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel bioactive molecules, including peptide mimetics and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated peptides and peptidomimetics for drug discovery programs.
• Agrochemical Research: Used in the development of novel, fluorinated active ingredients with potentially enhanced biological activity and stability.
• Biochemical Probe Synthesis: Employed to create fluorinated analogs of amino acids for studying enzyme mechanisms and protein interactions.
• Organic Synthesis Building Block: Serves as a versatile chiral synthon for constructing complex molecules in medicinal and process chemistry.
• Material Science Research: Investigated for incorporation into specialty polymers and advanced materials requiring specific stereochemical or fluorinated properties.

Basic Information

Product Name	L-Aspartic Acid, 3-Fluoro-, 4-Methyl Ester (9Ci)
CAS No.	766466-01-7
Molecular Formula	C5H8FNO4
Molecular Weight	165.12 g/mol
Synonyms	4-Methyl (3S)-3-fluoro-L-aspartate; (2S)-2-Amino-3-fluoro-4-methoxy-4-oxobutanoic Acid; 3-Fluoro-L-aspartic Acid 4-Methyl Ester; Methyl (2S)-2-amino-3-fluoro-4-oxo-4-methoxybutanoate; L-3-Fluoroaspartic Acid 4-Methyl Ester; (S)-2-Amino-3-fluoro-4-methoxy-4-oxobutanoic Acid; 3-Fluoro-L-aspartic Acid Methyl Ester; 766466-01-7
EINECS	Contact for details

Quality Control

Our L-Aspartic Acid, 3-Fluoro-, 4-Methyl Ester (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.