Description

2-Cyano-3-Fluorophenylboronic Acid Pinacol Ester is a high-value, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex fluorinated and cyanated aromatic systems. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing fluorinated and cyanated biaryl compounds with potential biological activity.
• Agrochemical Research: Used to create novel active ingredients for crop protection agents, leveraging the unique properties of fluorine and cyano groups.
• Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and other advanced functional materials requiring precise molecular architecture.
• Chemical Synthesis: Acts as a versatile reagent for introducing the 2-cyano-3-fluorophenyl moiety into complex molecular scaffolds under mild conditions.
• Library Synthesis: Valuable for medicinal chemistry programs focused on generating diverse compound libraries for high-throughput screening.

Basic Information

Product Name	2-Cyano-3-Fluorophenylboronic Acid Pinacol Ester
CAS No.	765916-91-4
Molecular Formula	C₁₃H₁₅BFNO₂
Molecular Weight	247.08 g/mol
Synonyms	2-Cyano-3-fluorobenzeneboronic acid pinacol ester; (2-Cyano-3-fluorophenyl)boronic acid pinacol ester; 3-Fluoro-2-cyanophenylboronic acid pinacol ester; 2-Fluoro-6-cyanophenylboronic acid pinacol ester; B-(2-Cyano-3-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 765916-91-4; Pinacol (2-cyano-3-fluorophenyl)boronate
EINECS	Contact for details

Quality Control

Our 2-Cyano-3-Fluorophenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, NMR, and mass spectrometry results. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.