Description

2-Desethyl-2-Propylazithromycin is a key semi-synthetic derivative of the macrolide antibiotic azithromycin, specifically engineered for advanced pharmaceutical research and development. This compound is valued for its role as a critical intermediate in the synthesis of novel antibiotic analogs, enabling the exploration of enhanced efficacy and reduced resistance profiles. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of next-generation antimicrobial agents and in-depth pharmacological studies.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel macrolide antibiotic derivatives.
• Antimicrobial Research: Used in R&D programs focused on overcoming bacterial resistance mechanisms and improving drug potency.
• Structure-Activity Relationship (SAR) Studies: Essential for investigating the impact of structural modifications on the biological activity of azithromycin analogs.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Process Chemistry: Utilized in the scale-up and optimization of synthetic routes for advanced antibiotic manufacturing.

Basic Information

Product Name	2-Desethyl-2-Propylazithromycin
CAS No.	763924-54-5
Molecular Formula	C40H78N2O12
Molecular Weight	779.06 g/mol
Synonyms	2-Desethyl-2-propylazithromycin; Azithromycin, 2-desethyl-2-propyl-; 2-Propyl-2-desethylazithromycin; 9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A, 2-desethyl-2-propyl derivative; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-Ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one; 2-Desethyl-2-propyl derivative of azithromycin
EINECS	Contact for details

Quality Control

Our 2-Desethyl-2-Propylazithromycin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC and NMR. We adhere to cGMP guidelines for the production of pharmaceutical intermediates to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.