Description

Piperidine, 2,6-Dimethyl-1-(1-Oxo-2-Propenyl)-, (2R,6S)-Rel- (9Ci) CAS NO 762287-47-8 is a high-purity, stereochemically defined piperidine derivative featuring an acryloyl functional group. This compound is a critical chiral building block and intermediate in advanced organic synthesis, valued for its structural complexity and defined stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic agents.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where specific stereochemistry can influence biological activity and environmental profile.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic and R&D Laboratories: Employed in methodological studies and the synthesis of complex natural product analogs or novel chemical entities.
• Fine Chemical Production: Utilized as a specialized intermediate for manufacturing high-value, low-volume chemicals with specific stereochemical requirements.

Basic Information

Product Name	Piperidine, 2,6-Dimethyl-1-(1-Oxo-2-Propenyl)-, (2R,6S)-Rel- (9Ci)
CAS No.	762287-47-8
Molecular Formula	C10H17NO
Molecular Weight	167.25 g/mol
Synonyms	(2R,6S)-2,6-Dimethyl-1-acryloylpiperidine; rel-(2R,6S)-2,6-Dimethyl-1-(prop-2-enoyl)piperidine; 1-Acryloyl-2,6-dimethylpiperidine (stereoisomer); 2,6-Dimethyl-1-acryloylpiperidine; (2R,6S)-2,6-Dimethyl-N-acryloylpiperidine; Acrylic acid (2R,6S)-2,6-dimethylpiperidide; A chiral piperidine acrylamide derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, GC, chiral analysis, and NMR to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.