Description

Acetamide, n-(2,4-Dihydroxyphenyl)-2,2,2-Trifluoro- (9Ci) is a specialized trifluoroacetamide derivative featuring a dihydroxyphenyl substituent, making it a valuable fluorinated building block. This compound is significant for its role in advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals where the introduction of fluorine atoms can dramatically alter biological activity and metabolic stability. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, material science, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in areas targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances lipophilicity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials due to its unique electronic properties imparted by the fluorine atoms.
• Chemical Biology Probe Development: Utilized in designing molecular probes and inhibitors for studying enzyme mechanisms and protein-ligand interactions.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, amide bond formations, and as a protected form of a catechol derivative in multi-step synthetic routes.

Basic Information

Product Name	Acetamide, n-(2,4-Dihydroxyphenyl)-2,2,2-Trifluoro- (9Ci)
CAS No.	761455-52-1
Molecular Formula	C8H6F3NO3
Molecular Weight	221.14 g/mol
Synonyms	N-(2,4-Dihydroxyphenyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(2,4-dihydroxyphenyl)acetamide; 2',4'-Dihydroxy-2,2,2-trifluoroacetophenone imide; 1-(2,4-Dihydroxyphenyl)-2,2,2-trifluoroethan-1-imine; TFA-protected 2,4-dihydroxyaniline; Trifluoroacetylamino resorcinol
EINECS	Contact for details

Quality Control

Our Acetamide, n-(2,4-Dihydroxyphenyl)-2,2,2-Trifluoro- (9Ci) is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.