Description

Oxazole, 2-[[2-(Diphenylphosphino)Phenyl]Methyl]-4,5-Dihydro-4-Phenyl-, (4S)- is a sophisticated chiral ligand and a key building block in advanced organic synthesis. This compound matters for its role in facilitating highly selective catalytic transformations, enabling the production of enantiomerically pure intermediates. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing novel active ingredients and high-value specialty chemicals.

Application

• As a chiral ligand in asymmetric catalysis, particularly for transition metal-catalyzed cross-coupling and hydrogenation reactions.
• A key pharmaceutical intermediate in the synthesis of enantiomerically pure drug candidates and active pharmaceutical ingredients (APIs).
• Building block for the development of novel organocatalysts and specialty materials with tailored properties.
• Used in academic and industrial R&D for methodological studies in organic and organometallic chemistry.
• Precursor in the synthesis of complex natural product analogs and other structurally intricate molecules.

Basic Information

Product Name	Oxazole, 2-[[2-(Diphenylphosphino)Phenyl]Methyl]-4,5-Dihydro-4-Phenyl-, (4S)-
CAS No.	761402-27-1
Molecular Formula	C28H24NOP
Molecular Weight	421.47 g/mol
Synonyms	(4S)-2-[[2-(Diphenylphosphino)Phenyl]Methyl]-4,5-Dihydro-4-Phenyloxazole; (S)-2-((2-(Diphenylphosphino)benzyl)-4,5-dihydro-4-phenyloxazole; (S)-PHOX Ligand derivative; Chiral Oxazoline-Phosphine Ligand; P,N-Ligand; Asymmetric Catalyst Ligand; (S)-2-[(2-Diphenylphosphinophenyl)methyl]-4-phenyl-4,5-dihydrooxazole; 761402-27-1
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, chiral purity, and chemical purity. Certificates of Analysis (COA) detailing specific results for assay, enantiomeric excess, and impurity profiles are available upon request. We adhere to strict quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed under an inert atmosphere to prevent degradation. Handle and store in accordance with all applicable regulations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.