Description

2-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is a high-value, functionalized phenol derivative containing a boronic ester pinacol group, making it a versatile and critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, scalable intermediates for developing active ingredients, functional polymers, and liquid crystal compounds. The CAS number for this product is 760990-08-7.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biaryl or substituted phenol motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides through cross-coupling strategies.
• Material Science: Serves as a monomer or functionalization agent in the production of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: An indispensable reagent in medicinal chemistry and process chemistry for library synthesis and route scouting.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.

Basic Information

Item	Details
Product Name	2-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol
CAS No.	760990-08-7
Molecular Formula	C12H16BFO3
Molecular Weight	238.07 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-fluorophenol; 2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol; 2-Fluoro-4-pinacolborylphenol; 4-Borono-2-fluorophenol pinacol ester; (2-Fluoro-4-hydroxyphenyl)boronic acid pinacol ester; 760990-08-7; 2-Fluoro-4-(pinacolatoboryl)phenol
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our standard quality commitment includes comprehensive analysis via HPLC, NMR, and GC-MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.