Description

Bicyclo[2.2.1]Heptane-2-Carbonitrile, 5-Amino-2-Methyl-, (2-Endo,5-Exo)- (9Ci) is a high-purity, stereochemically defined bicyclic nitrile building block, essential for advanced organic synthesis. Its rigid norbornane skeleton and strategically positioned amino and nitrile functional groups make it a versatile chiral intermediate for constructing complex molecular architectures. This compound is primarily needed by R&D and process chemistry teams in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used as a building block for creating advanced, stereospecific pesticides and herbicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with unique structural properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and for exploring new chemical spaces in discovery programs.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2-Carbonitrile, 5-Amino-2-Methyl-, (2-Endo,5-Exo)- (9Ci)
CAS No.	759421-43-7
Molecular Formula	C9H14N2
Molecular Weight	150.22 g/mol
Synonyms	(2-endo,5-exo)-5-Amino-2-methylbicyclo[2.2.1]heptane-2-carbonitrile; 5-Amino-2-methyl-2-norbornanecarbonitrile (endo,exo); 2-Norbornanecarbonitrile, 5-amino-2-methyl-, (2-endo,5-exo)-; Amino-methyl-norbornanecarbonitrile; Chiral norbornane nitrile; Bicyclo[2.2.1]heptane-2-carbonitrile, 5-amino-2-methyl-, endo,exo- isomer
EINECS	Contact for details

Quality Control

Every batch of our Bicyclo[2.2.1]Heptane-2-Carbonitrile, 5-Amino-2-Methyl-, (2-Endo,5-Exo)- (9Ci) is produced and controlled under a strict quality management system. We ensure high chiral purity and chemical integrity through advanced analytical techniques including chiral HPLC, NMR, and GC-MS. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.