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Di-tert-Butyl-2-Norbornylphosphine CAS NO 758699-76-2


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CAS No.:758699-76-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Di-tert-Butyl-2-Norbornylphosphine is a specialized, sterically hindered tertiary phosphine ligand of significant interest in advanced catalytic chemistry. Its unique norbornyl backbone and bulky tert-butyl substituents confer exceptional electronic and steric properties, making it a valuable tool for modulating catalyst activity and selectivity. This high-purity organophosphorus compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for developing novel synthetic methodologies and optimizing transition metal-catalyzed reactions.

Application

  • As a ligand in cross-coupling reactions (e.g., Suzuki-Miyaura, Buchwald-Hartwig amination) for C-C and C-N bond formation.
  • Employed in homogeneous catalysis for hydrogenation, hydroformylation, and hydrosilylation processes.
  • Used in academic and industrial R&D to explore new catalytic systems and reaction mechanisms.
  • Facilitates the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
  • Applied in the development of agrochemicals and specialty fine chemicals requiring precise stereochemical control.
  • Serves as a precursor or modifying agent for advanced materials and polymer catalysts.

Basic Information

Product Name Di-tert-Butyl-2-Norbornylphosphine
CAS No. 758699-76-2
Molecular Formula C15H29P
Molecular Weight 240.36 g/mol
Synonyms 2-(Di-tert-butylphosphino)norbornane; Norbornane, 2-(bis(1,1-dimethylethyl)phosphino)-; Di-tert-butyl(norbornan-2-yl)phosphine; Di-t-butyl-2-norbornylphosphine; DTBNp; 2-Norbornyl-di-tert-butylphosphine
EINECS Contact for details

Quality Control

Our Di-tert-Butyl-2-Norbornylphosphine is manufactured under stringent quality management systems to ensure batch-to-batch consistency and high purity, typically ≥97% (by NMR or HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity confirmation, and impurity profile. We support custom synthesis and purity grades to meet specific research or process development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should only be opened in an inert environment.

Specification

Item Specification
Appearance White to off-white solid
Identification (NMR) Conforms to structure
Purity (HPLC/NMR) ≥ 97.0%
Melting Point Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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