Description

Cyclopentanecarboxylic Acid, 3-Amino-4-(Fluoromethylene)-, (1S,3S,4Z)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters for its unique structural features, including a cyclopentane ring, an amino group, and a fluoromethylene unit, which are critical for modulating the biological activity and physicochemical properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry programs targeting enzyme inhibition and receptor modulation.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in areas requiring fluorinated analogs to improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the creation of advanced, target-specific pesticides and herbicides where the fluorine atom and specific stereochemistry enhance activity and environmental profile.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing complex molecular libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Fluorine Chemistry: An important reagent for introducing fluorinated motifs into organic molecules, a growing field in material and life sciences.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of fine chemicals and active pharmaceutical ingredients (APIs).
• Bioconjugation & Probe Development: Potential use in developing biochemical probes and diagnostic agents due to its reactive amino group and fluorine label.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 3-Amino-4-(Fluoromethylene)-, (1S,3S,4Z)- (9Ci)
CAS No.	757942-70-4
Molecular Formula	C7H10FNO2
Molecular Weight	159.16 g/mol
Synonyms	(1S,3S,4Z)-3-Amino-4-(fluoromethylene)cyclopentanecarboxylic acid; (1S,3S,4Z)-3-Amino-4-(fluoromethylene)cyclopentane-1-carboxylic acid; 3-Amino-4-(fluoromethylene)cyclopentanecarboxylic acid, (1S,3S,4Z)-; (1S,3S,4Z)-3-Amino-4-(fluoromethylidene)cyclopentane-1-carboxylic acid; 757942-70-4; (1S,3S,4Z)-rel-3-Amino-4-(fluoromethylene)cyclopentanecarboxylic Acid; A fluorinated cyclopentane amino acid derivative
EINECS	Contact for details

Quality Control

Our production of Cyclopentanecarboxylic Acid, 3-Amino-4-(Fluoromethylene)-, (1S,3S,4Z)- (9Ci) adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized and tested to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) are provided, detailing key parameters such as assay (HPLC), chiral purity, and impurity profiles. We support cGMP compliance for advanced intermediates and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.