Description

Benzonitrile, 2-Chloro-4-Iodo-3-Methyl- CAS NO 757247-75-9 is a halogenated benzonitrile derivative, a versatile and highly functionalized aromatic nitrile building block. Its unique structure, featuring chlorine, iodine, and methyl substituents, makes it a critical intermediate for synthesizing complex molecules in advanced research and development. This compound is primarily sought by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients, as well as by material scientists developing specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for functionalized monomers in the synthesis of specialty polymers, dyes, and liquid crystalline materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitution reactions due to the reactivity of the chloro and iodo groups.
• Chemical Research & Development: Utilized in academic and industrial labs for exploring new synthetic methodologies and creating complex molecular architectures.

Basic Information

Product Name	Benzonitrile, 2-Chloro-4-Iodo-3-Methyl-
CAS No.	757247-75-9
Molecular Formula	C8H5ClIN
Molecular Weight	277.49 g/mol
Synonyms	2-Chloro-4-iodo-3-methylbenzonitrile; 3-Methyl-2-chloro-4-iodobenzonitrile; 2-Chloro-4-iodo-3-methyl-benzonitrile; Benzonitrile, 2-chloro-4-iodo-3-methyl-; (2-Chloro-4-iodo-3-methylphenyl)carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Iodo-3-Methylbenzonitrile is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residue on Ignition	<0.1%
Related Substances (HPLC)	Total impurities <3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.