Description

Cyclopentanecarboxylic Acid, 2-Amino-3-Methyl-, (1S,2S,3R)- (9Ci) CAS NO 757186-25-7 is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in its rigid cyclopentane scaffold and functional groups, which are crucial for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where specific stereochemistry is required for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in areas targeting central nervous system (CNS) disorders, antiviral agents, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of novel, stereoselective pesticides and herbicides where the specific spatial orientation of the molecule enhances efficacy and selectivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and catalysts used in enantioselective synthesis.
• Peptidomimetics & Conformationally Restricted Analogues: The cyclopentane core is valuable for designing and synthesizing peptide mimics and other bioactive compounds with improved metabolic stability and receptor binding profiles.
• Academic & Industrial R&D: Employed in chemical research laboratories for methodological studies in stereocontrolled synthesis and the exploration of new chemical spaces.
• Fine Chemical Production: Used in the custom synthesis of specialty chemicals for various high-value industrial applications.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-Amino-3-Methyl-, (1S,2S,3R)- (9Ci)
CAS No.	757186-25-7
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(1S,2S,3R)-2-Amino-3-methylcyclopentanecarboxylic acid; (1S,2S,3R)-2-Amino-3-methyl-1-cyclopentanecarboxylic acid; (1S,2S,3R)-AMCP; trans-2-Amino-3-methylcyclopentanecarboxylic acid (specific isomer); 2-Amino-3-methylcyclopentane-1-carboxylic acid; Chiral cyclopentane amino acid; Stereoisomer of 2-Amino-3-methylcyclopentanecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to strict quality management protocols. Every batch is characterized using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry to confirm identity, stereochemical purity (enantiomeric excess), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.