Description

Benzamide, 4-(1-Aminoethyl)-3-Hydroxy-n-4-Pyridinyl-, (R)- (9Ci) is a high-purity, chiral organic compound of significant interest in advanced pharmaceutical research and development. Its specific stereochemistry and functional groups make it a valuable key intermediate for synthesizing complex, biologically active molecules. This compound is primarily utilized by pharmaceutical companies and contract research organizations (CROs) engaged in the discovery of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Asymmetric Synthesis: Used in catalytic and stoichiometric asymmetric reactions to introduce the (R)-configured aminoethyl side chain into target molecules.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to develop new drug candidates.
• Chemical Biology Probes: Acts as a precursor for developing molecular probes to study enzyme function and biological pathways.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant scale for clinical trial material production.

Basic Information

Product Name	Benzamide, 4-(1-Aminoethyl)-3-Hydroxy-n-4-Pyridinyl-, (R)- (9Ci)
CAS No.	757165-17-6
Molecular Formula	C14H15N3O2
Molecular Weight	257.29 g/mol
Synonyms	(R)-4-(1-Aminoethyl)-3-hydroxy-N-(pyridin-4-yl)benzamide; 4-[(1R)-1-Aminoethyl]-3-hydroxy-N-4-pyridinylbenzamide; (R)-3-Hydroxy-4-(1-aminoethyl)-N-(pyridin-4-yl)benzamide; 4-(1-Aminoethyl)-3-hydroxy-N-(4-pyridinyl)benzamide, (R)-; Benzamide, 4-(1-aminoethyl)-3-hydroxy-N-4-pyridinyl-, (R)-; (R)-4-(1-Aminoethyl)-3-hydroxy-N-(4-pyridyl)benzamide
EINECS	Contact for details

Quality Control

Our Benzamide, 4-(1-Aminoethyl)-3-Hydroxy-n-4-Pyridinyl-, (R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral assay, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.