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Z-15-Amino-4,7,10,13-Tetraoxapentadecacanoic Acid CAS NO 756526-00-8
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CAS No.:756526-00-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Z-15-Amino-4,7,10,13-Tetraoxapentadecacanoic Acid is a specialized polyether amino acid derivative, featuring a hydrophilic tetraethylene glycol spacer terminated with a carboxylic acid group. This unique bifunctional structure makes it a valuable PEG-based linker for bioconjugation and the synthesis of complex molecular architectures. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotech, and advanced materials sectors for developing drug delivery systems, diagnostic agents, and functionalized surfaces.
Application
- Bioconjugation and PEGylation: A key building block for attaching drugs, proteins, or peptides to polyethylene glycol (PEG) chains to improve solubility, stability, and pharmacokinetics.
- Linker for Drug-Delivery Systems: Used in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutic constructs.
- Surface Functionalization: Modifying nanoparticles, quantum dots, or biosensor surfaces to introduce carboxylic acid groups for further coupling reactions.
- Polymer Chemistry: Serves as a monomer or chain extender for creating functionalized, water-soluble polymers and hydrogels.
- Diagnostic Reagent Synthesis: Incorporating into fluorescent probes, MRI contrast agents, or other imaging molecules.
- Intermediate for Specialty Chemicals: A versatile intermediate for synthesizing more complex, custom PEG derivatives and ligands.
Basic Information
| Product Name | Z-15-Amino-4,7,10,13-Tetraoxapentadecacanoic Acid |
| CAS No. | 756526-00-8 |
| Molecular Formula | C16H31NO7 |
| Molecular Weight | 349.42 g/mol |
| Synonyms | 15-Amino-4,7,10,13-tetraoxapentadecanoic Acid; Fmoc-NH-PEG4-CH2CH2COOH; N-α-Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic acid; Fmoc-PEG4-acid; Fmoc-15-amino-4,7,10,13-tetraoxapentadecanoic Acid; N-(9-Fluorenylmethoxycarbonyl)-15-amino-4,7,10,13-tetraoxapentadecanoic Acid; Fmoc-N-amido-PEG4-acid; PEG-based amino acid linker |
| EINECS | Contact for details |
Quality Control
Our Z-15-Amino-4,7,10,13-Tetraoxapentadecacanoic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical specifications. Our quality system supports compliance with cGMP and ISO standards for research and commercial applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive); containers must be sealed under inert atmosphere or with desiccant after opening to prevent degradation. For long-term storage, keep under nitrogen at -20°C.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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