Description

Mc-Phe-Lys(Boc)-Pab CAS NO 756487-18-0 is a protected peptide building block, specifically a Boc-protected lysine derivative coupled to a para-aminobenzoic acid (Pab) linker. This compound is a critical intermediate for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics, enabling precise control over molecular architecture. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers developing novel therapeutic agents, diagnostic probes, and advanced biomaterials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Peptidomimetic Research: Used to create modified peptide structures with enhanced stability, bioavailability, or target specificity.
• Linker Chemistry: The para-aminobenzoic acid (Pab) moiety serves as a versatile spacer or cleavable linker in prodrug design and bioconjugation.
• Combinatorial Chemistry: Essential reagent in libraries for high-throughput screening to identify new bioactive compounds.
• Bioconjugation Probes: Facilitates the attachment of peptides to other molecules, such as fluorophores, drugs, or solid supports, for diagnostic and research applications.
• Academic & Institutional R&D: Supports fundamental research in medicinal chemistry, chemical biology, and proteomics.

Basic Information

Product Name	Mc-Phe-Lys(Boc)-Pab
CAS No.	756487-18-0
Molecular Formula	C31H43N5O6
Molecular Weight	581.71 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalanyl-N6-[(1,1-dimethylethoxy)carbonyl]-L-lysyl-4-aminobenzoic acid; Fmoc-Phe-Lys(Boc)-Pab-OH; Fmoc-L-Phe-L-Lys(Boc)-4-Abz-OH; N-α-Fmoc-N-ε-Boc-L-lysyl-L-phenylalanyl-4-aminobenzoic acid; Boc-Lys(Phe-Fmoc)-Pab; Peptide Building Block 756487-18-0; Fmoc-Phe-Lys(Boc)-4-Abz
EINECS	Contact for details

Quality Control

Our Mc-Phe-Lys(Boc)-Pab is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -15°C. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Single Impurity (HPLC)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.