Description

3-Iodo-Benzamidine is a valuable halogenated benzamidine derivative, serving as a key chemical intermediate and building block in advanced organic synthesis. Its significance lies in its reactive amidine group and iodine substituent, which make it a versatile precursor for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as medicinal chemistry and the synthesis of protease inhibitors.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting serine proteases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides, leveraging its halogenated aromatic structure.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes (ABPs) for studying enzyme function and inhibition.
• Peptidomimetic Development: Incorporated into the backbone of peptidomimetics to enhance stability and bioavailability of peptide-based compounds.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated amidines.

Basic Information

Product Name	3-Iodo-Benzamidine
CAS No.	756434-74-9
Molecular Formula	C7H7IN2
Molecular Weight	246.05 g/mol
Synonyms	3-Iodobenzamidine; Benzenecarboximidamide, 3-iodo-; 3-Iodo-benzenecarboximidamide; m-Iodobenzamidine; 3-Iodophenylamidine; 756434-74-9; Amidino-3-iodobenzene
EINECS	Contact for details

Quality Control

Our 3-Iodo-Benzamidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.