Description

Pseudoephedrine-D3 is a stable isotope-labeled analog of pseudoephedrine, specifically deuterated at three positions. This compound is essential as an internal standard in quantitative analytical methods, providing unmatched accuracy and reliability for mass spectrometry-based measurements. It is primarily required by pharmaceutical research laboratories, forensic toxicology units, and analytical service providers engaged in drug metabolism studies, pharmacokinetic research, and the precise quantification of pseudoephedrine in complex biological matrices.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis of pseudoephedrine.
• Quantitative bioanalysis in clinical and preclinical pharmacokinetic studies.
• Metabolite identification and drug metabolism research (DMPK).
• Forensic analysis and toxicology screening for accurate substance quantification.
• Quality control and method validation in pharmaceutical manufacturing.
• Stable isotope dilution assays for high-precision measurement.
• Research into the pharmacological activity and disposition of sympathomimetic amines.

Basic Information

Product Name	Pseudoephedrine-D3
CAS No.	754966-06-8
Molecular Formula	C10H12D3NO
Molecular Weight	~166.25 g/mol
Synonyms	(1S,2S)-2-(Methyl-d3-amino)-1-phenylpropan-1-ol; d3-Pseudoephedrine; [2H3]-Pseudoephedrine; Pseudoephedrine (methyl-d3); (+)-ψ-Ephedrine-d3; (1S,2S)-Pseudoephedrine-d3; Isotopically Labeled Pseudoephedrine
EINECS	Contact for details

Quality Control

Our Pseudoephedrine-D3 is manufactured under strict quality systems to ensure high chemical and isotopic purity, critical for its role as an analytical standard. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity by HPLC, and identity confirmation. We adhere to relevant industry guidelines for stable isotope-labeled compounds to guarantee consistency and reliability for your sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (by NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.