Description

Gal Beta(1-3)[Neu5Ac Alpha(2-6)]Glcnac-β-Pnp is a synthetic, para-nitrophenyl (pNP)-tagged oligosaccharide derivative, specifically designed as a high-purity enzymatic substrate and research standard. This compound is critical for studying glycosidase and glycosyltransferase activities, particularly those involved in sialylated glycan biosynthesis and catabolism. It is an essential reagent for researchers and developers in glycobiology, enzymology, and pharmaceutical discovery, enabling precise biochemical assays and the development of diagnostic tools.

Application

• Glycosidase Enzyme Assays: Primary substrate for measuring the activity of specific β-galactosidases and neuraminidases (sialidases) in kinetic studies.
• Glycosyltransferase Research: Used as an acceptor molecule in studies to characterize the function of sialyltransferases and other enzymes in glycan synthesis pathways.
• Diagnostic Reagent Development: Serves as a key component in developing colorimetric or fluorogenic assays for enzyme-linked detection systems used in clinical and research diagnostics.
• Inhibitor Screening: Essential tool for high-throughput screening (HTS) campaigns to identify and characterize novel enzyme inhibitors for therapeutic applications.
• Biochemical Standard: Provides a well-defined reference standard for the quantification and validation of enzymatic processes in complex biological samples.
• Glycan Array Fabrication: Can be utilized in the synthesis of neoglycoconjugates for immobilization on surfaces to study protein-carbohydrate interactions.

Basic Information

Product Name	Gal Beta(1-3)[Neu5Ac Alpha(2-6)]Glcnac-β-Pnp
CAS No.	754954-71-7
Molecular Formula	C31H43N3O21
Molecular Weight	793.68 g/mol
Synonyms	Galβ1-3(Neu5Acα2-6)GlcNAc-β-pNP; p-Nitrophenyl N-acetyl-β-D-lactosaminide derivative; 4-Nitrophenyl 6'-sialyl-N-acetyllactosaminide; Sialyl Lewis x precursor analog; pNP-6'-Sialyl-N-acetyllactosamine; Oligosaccharide-pNP conjugate; Glycosidase substrate 754954-71-7; Enzymatic substrate for neuraminidase
EINECS	Contact for details

Quality Control

Every batch of Gal Beta(1-3)[Neu5Ac Alpha(2-6)]Glcnac-β-Pnp is manufactured and analyzed under strict quality protocols to ensure identity, purity, and performance consistency for sensitive research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting research standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (HPLC)	≥ 98% (on dried basis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.