Description

2-(1-Aminocyclopentyl)Acetonitrile is a versatile chiral nitrile building block of significant interest in advanced organic synthesis. Its structure, featuring both a cyclopentyl amine and an acetonitrile moiety, makes it a critical intermediate for constructing complex molecules with high stereochemical control. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multistep synthesis of specialty chemicals, flavors, and fragrances requiring precise molecular architecture.
• Academic and Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	2-(1-Aminocyclopentyl)Acetonitrile
CAS No.	753023-64-2
Molecular Formula	C7H12N2
Molecular Weight	124.18 g/mol
Synonyms	1-(Cyanomethyl)cyclopentanamine; (1-Aminocyclopentyl)acetonitrile; 2-(1-Aminocyclopentyl)ethanenitrile; 1-Aminocyclopentaneacetonitrile; Cyclopentanamine, 1-(cyanomethyl)-; 753023-64-2; Aminocyclopentylacetonitrile
EINECS	Contact for details

Quality Control

Our 2-(1-Aminocyclopentyl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the exacting standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.