Description

Benzamide, n-(cis-4-Aminocyclohexyl)-2-Hydroxy-5-Methyl- (9Ci) is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry. This compound is critical for the research and development of novel therapeutic agents, particularly in oncology and targeted drug delivery systems. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of targeted kinase inhibitors and other small-molecule APIs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Process Chemistry Development: Serves as a critical starting material for scaling up synthetic routes under GMP conditions.
• Bioconjugation: Potential use in the development of antibody-drug conjugates (ADCs) and other targeted biologics.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis: Base compound for the custom manufacturing of proprietary derivatives and analogs.

Basic Information

Product Name	Benzamide, n-(cis-4-Aminocyclohexyl)-2-Hydroxy-5-Methyl- (9Ci)
CAS No.	752981-36-5
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	N-[(1s,4s)-4-Aminocyclohexyl]-2-hydroxy-5-methylbenzamide; (cis)-4-Amino-N-(2-hydroxy-5-methylbenzoyl)cyclohexanamine; 2-Hydroxy-5-methyl-N-[(1s,4s)-4-aminocyclohexyl]benzamide; 4-Amino-N-(2-hydroxy-5-methylbenzoyl)cyclohexanamine (cis); Benzamide, N-(cis-4-aminocyclohexyl)-2-hydroxy-5-methyl-; 752981-36-5; cis-4-[(2-Hydroxy-5-methylbenzoyl)amino]cyclohexanamine
EINECS	Contact for details

Quality Control

Our Benzamide, n-(cis-4-Aminocyclohexyl)-2-Hydroxy-5-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with client specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (cis-isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.