Description

(1R,3R)-3-(((Benzyloxy)Carbonyl)Amino)Cyclohexyl Acetate is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex, biologically active molecules, offering precise stereochemical control. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetic Chemistry: Serves as a constrained, stereodefined scaffold for constructing peptide analogs and mimetics to enhance metabolic stability and bioavailability.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric transformations to introduce the (1R,3R) stereochemistry into more complex molecular architectures.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization campaigns to explore novel chemical space.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-fidelity chiral building blocks under cGMP or non-GMP conditions.
• Chemical Biology Probes: Used in the synthesis of labeled compounds or molecular probes for investigating biological pathways and target engagement.

Basic Information

Product Name	(1R,3R)-3-(((Benzyloxy)Carbonyl)Amino)Cyclohexyl Acetate
CAS No.	750649-42-4
Molecular Formula	C16H21NO4
Molecular Weight	291.34 g/mol
Synonyms	(1R,3R)-3-[[(Benzyloxy)carbonyl]amino]cyclohexyl acetate; (1R,3R)-3-(Cbz-Amino)cyclohexyl Acetate; (1R,3R)-3-[(Carbobenzyloxy)amino]cyclohexyl acetate; (1R,3R)-3-(N-Cbz-amino)cyclohexyl acetate; Cyclohexanol, 3-[[(phenylmethoxy)carbonyl]amino]-, 1-acetate, (1R,3R)-; Z-ACHC-OAc; Cbz-NH-ACHC-OAc
EINECS	Contact for details

Quality Control

Our (1R,3R)-3-(((Benzyloxy)Carbonyl)Amino)Cyclohexyl Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.