Description

3,5-Methano-2H-Cyclopenta[B]Furan-2-One,6-Fluorohexahydro-(9Ci) is a specialized fluorinated bicyclic lactone building block of significant interest in advanced organic synthesis. Its unique fused ring structure and fluorine substituent make it a valuable precursor for creating complex molecular architectures with tailored properties. This high-purity intermediate is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom and rigid bicyclic core can enhance biological activity and environmental stability.
• Advanced Material Precursor: Acts as a monomer or specialty additive in the synthesis of performance polymers and liquid crystals, contributing unique steric and electronic characteristics.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research focused on developing new catalytic methodologies.
• Fluorine Chemistry Studies: A valuable compound for investigating structure-activity relationships (SAR) and the effects of fluorination in complex molecular systems.

Basic Information

Product Name	3,5-Methano-2H-Cyclopenta[B]Furan-2-One,6-Fluorohexahydro-(9Ci)
CAS No.	750569-89-2
Molecular Formula	C8H9FO2
Molecular Weight	156.16 g/mol
Synonyms	6-Fluorohexahydro-3,5-methano-2H-cyclopenta[b]furan-2-one; (1R,3S,5R,6S)-6-Fluoro-3,7-dioxatricyclo[3.3.0.03,5]octan-4-one; Hexahydro-6-fluoro-3,5-methano-2H-cyclopenta[b]furan-2-one; 6-Fluoro-3,7-dioxatricyclo[3.3.0.0³,⁵]octan-4-one; Fluorinated bicyclic lactone; 750569-89-2
EINECS	Contact for details

Quality Control

Our 3,5-Methano-2H-Cyclopenta[B]Furan-2-One,6-Fluorohexahydro-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.