Description

2-Propen-1-One, 2-Fluoro-3-Hydroxy-1-(4-Methylphenyl)- (9Ci) is a specialized fluorinated aromatic ketone building block, identified by CAS number 750509-46-7. This compound is valued for its unique molecular scaffold, which incorporates both a reactive α,β-unsaturated ketone moiety and a fluorine substituent, making it a versatile intermediate for advanced synthetic chemistry. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, especially those targeting specific enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, or insecticides where the fluorinated aromatic structure can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for advanced polymers or specialty chemicals where the introduction of fluorine atoms can alter material properties like solubility, thermal stability, or surface energy.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological processes, leveraging its reactive enone functionality for bioconjugation.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological development and exploration of new synthetic pathways.

Basic Information

Product Name	2-Propen-1-One, 2-Fluoro-3-Hydroxy-1-(4-Methylphenyl)- (9Ci)
CAS No.	750509-46-7
Molecular Formula	C10H9FO2
Molecular Weight	180.18 g/mol
Synonyms	2-Fluoro-3-hydroxy-1-(4-methylphenyl)prop-2-en-1-one; 1-(4-Methylphenyl)-2-fluoro-3-hydroxy-2-propen-1-one; 2-Fluoro-3-hydroxy-1-p-tolylprop-2-en-1-one; 750509-46-7; 2-Fluoro-3-hydroxy-1-(4-methylphenyl)prop-2-en-1-one (9CI); 2-Propen-1-one, 2-fluoro-3-hydroxy-1-(4-methylphenyl)-; p-Tolyl 2-fluoro-3-hydroxypropenone
EINECS	Contact for details

Quality Control

Our production of 2-Propen-1-One, 2-Fluoro-3-Hydroxy-1-(4-Methylphenyl)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, NMR and IR for structural confirmation, and GC/MS for impurity profiling. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere if specified for high-purity grades to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.