Description

Benzamide, n-(3-Cyano-2-Thienyl)-4-Fluoro- (9Ci) CAS NO 749919-77-5 is a specialized heterocyclic amide compound featuring a thiophene ring substituted with a cyano group and a fluorinated benzamide moiety. This unique molecular architecture makes it a valuable high-purity building block for advanced chemical synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Research: Serves as a core scaffold for creating novel herbicides, fungicides, or insecticides, leveraging the bioactivity of the thienyl and fluorinated benzamide groups.
• Material Science: Used in the synthesis of advanced organic materials, such as organic semiconductors or liquid crystals, where its conjugated system and specific substituents can tune electronic properties.
• Chemical Biology Probe: Employed in academic and industrial labs to develop molecular probes for studying enzyme function or protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	Benzamide, n-(3-Cyano-2-Thienyl)-4-Fluoro- (9Ci)
CAS No.	749919-77-5
Molecular Formula	C12H7FN2OS
Molecular Weight	246.26 g/mol
Synonyms	4-Fluoro-N-(3-cyano-2-thienyl)benzamide; N-(3-Cyano-2-thienyl)-4-fluorobenzamide; 4-Fluoro-N-(3-cyano-2-thienyl)benzamide (9CI); Benzamide, 4-fluoro-N-(3-cyano-2-thienyl)-; 749919-77-5; 4-Fluoro-N-(3-cyano-thiophen-2-yl)-benzamide
EINECS	Contact for details

Quality Control

Our Benzamide, n-(3-Cyano-2-Thienyl)-4-Fluoro- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high-purity standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.