Description

Cyclopropanecarboxamide, 2-(Hydroxymethyl)-n-Methoxy-n-Methyl-, (1R,2R)-Rel- (9Ci) is a high-purity, stereochemically defined chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex, biologically active molecules, offering precise control over molecular architecture. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical integrity is paramount.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new therapeutic agents, particularly in areas requiring complex cyclopropane-containing scaffolds.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents where specific stereochemistry enhances efficacy and selectivity.
• Chemical Research: Serves as a valuable reagent in academic and industrial laboratories for methodological studies in asymmetric synthesis and organometallic chemistry.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that utilize chiral cyclopropane motifs.
• Process Chemistry Development: Acts as a model compound for scaling up stereoselective synthetic routes under Current Good Manufacturing Practice (cGMP) conditions.

Basic Information

Product Name	Cyclopropanecarboxamide, 2-(Hydroxymethyl)-n-Methoxy-n-Methyl-, (1R,2R)-Rel- (9Ci)
CAS No.	749885-56-1
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	(1R,2R)-rel-2-(Hydroxymethyl)-N-methoxy-N-methylcyclopropanecarboxamide; N-Methoxy-N-methyl-2-(hydroxymethyl)cyclopropanecarboxamide (rel-(1R,2R)-); 2-(Hydroxymethyl)-N-methoxy-N-methylcyclopropanecarboxamide (rel-(1R,2R)-); Cyclopropanecarboxamide, 2-(hydroxymethyl)-N-methoxy-N-methyl-, (1R,2R)-rel-; 749885-56-1; Chiral Weinreb Amide Cyclopropane Derivative; Hydroxymethyl Cyclopropane Weinreb Amide.
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxamide, 2-(Hydroxymethyl)-n-Methoxy-n-Methyl-, (1R,2R)-Rel- (9Ci) is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.