Description

2-Chloro-1,3-Difluoro-4-(Methoxymethoxy)Benzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. Its unique structure, featuring halogen and protected hydroxyl substituents, makes it a critical intermediate for constructing complex molecules with precise electronic and steric properties. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking reliable, high-quality raw materials for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorinated benzene core with orthogonal reactivity for further functionalization.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the chloro and fluoro substituents contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, where its aromatic structure and halogen atoms are utilized to tune electronic properties and molecular alignment.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers with enhanced thermal and chemical resistance.
• Organic Synthesis Building Block: The methoxymethoxy (MOM) protecting group offers synthetic flexibility, making it valuable for multi-step organic synthesis in academic and industrial research.
• Fluorine Chemistry Research: An important compound for studying the effects of fluorine substitution on aromatic systems and developing new fluorination methodologies.

Basic Information

Product Name	2-Chloro-1,3-Difluoro-4-(Methoxymethoxy)Benzene
CAS No.	749230-34-0
Molecular Formula	C8H7ClF2O2
Molecular Weight	208.59 g/mol
Synonyms	1-Chloro-2,4-difluoro-5-(methoxymethoxy)benzene; 2,4-Difluoro-5-(methoxymethoxy)chlorobenzene; 4-(Methoxymethoxy)-2-chloro-1,3-difluorobenzene; Benzene, 2-chloro-1,3-difluoro-4-(methoxymethoxy)-; 749230-34-0; 2-Chloro-1,3-difluoro-4-(methoxymethoxy)benzene; 2-Chloro-1,3-difluoro-4-methoxymethoxybenzene
EINECS	Contact for details

Quality Control

Our 2-Chloro-1,3-Difluoro-4-(Methoxymethoxy)Benzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We support customer audits and can provide material to meet the stringent requirements of cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.