Description

1,3-Difluoro-5-(Methoxymethoxy)Benzene is a high-value fluorinated aromatic building block characterized by its unique substitution pattern. This compound is essential for introducing specific fluorine atoms and protected hydroxyl functionalities into complex molecular architectures, enabling precise control over electronic and steric properties. It is primarily sought after by R&D and process development chemists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity, stability, and metabolic resistance.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing components in electronic display materials, contributing to improved performance and durability.
• Polymer Chemistry: Employed as a monomer or modifier to create specialty polymers with enhanced chemical resistance, thermal stability, and specific surface properties.
• Cross-Coupling Reactions: An effective substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Protecting Group Chemistry: The methoxymethoxy (MOM) group acts as a robust protecting group for phenols, which can be selectively deprotected under mild acidic conditions.

Basic Information

Product Name	1,3-Difluoro-5-(Methoxymethoxy)Benzene
CAS No.	749230-20-4
Molecular Formula	C9H10F2O2
Molecular Weight	188.17 g/mol
Synonyms	5-(Methoxymethoxy)-1,3-difluorobenzene; 1,3-Difluoro-5-(methoxymethoxy)benzene; 3,5-Difluorophenyl methoxymethyl ether; Benzene, 1,3-difluoro-5-(methoxymethoxy)-; MOM-ether of 3,5-difluorophenol
EINECS	Contact for details

Quality Control

Every batch of 1,3-Difluoro-5-(Methoxymethoxy)Benzene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by GC, HPLC, and NMR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.