Description

2,5-Difluoro-1-(Methoxymethoxy)Benzene is a versatile fluorinated aromatic ether building block of significant interest in advanced organic synthesis. Its unique structure, featuring both fluorine atoms and a protected hydroxyl group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the difluoro and methoxymethoxy groups contribute to biological activity and selectivity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter physical properties such as chemical resistance, thermal stability, and surface energy.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Stille) due to the presence of fluorine atoms, enabling further functionalization.
• Protecting Group Chemistry: The methoxymethoxy (MOM) group can be used as a protective strategy for phenols in multi-step synthetic sequences.

Basic Information

Item	Detail
Product Name	2,5-Difluoro-1-(Methoxymethoxy)Benzene
CAS No.	749230-16-8
Molecular Formula	C9H10F2O2
Molecular Weight	188.17 g/mol
Synonyms	1,4-Difluoro-2-(methoxymethoxy)benzene; 2,5-Difluorophenyl methoxymethyl ether; 2-(Methoxymethoxy)-1,4-difluorobenzene; Benzene, 2,5-difluoro-1-(methoxymethoxy)-; MOM ether of 2,5-difluorophenol; 2,5-Difluorophenyl MOM ether
EINECS	Contact for details

Quality Control

Every batch of 2,5-Difluoro-1-(Methoxymethoxy)Benzene is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.