Description

2-Chloro-4-Trifluoromethoxy-Benzenesulfonyl Chloride is a high-purity, multi-functional chemical intermediate essential for advanced synthesis. This compound matters for its role as a key building block in the development of complex, high-value molecules, particularly in regulated industries. It is primarily needed by research institutions and manufacturers in the agrochemical and pharmaceutical sectors for creating novel active ingredients and fine chemicals.

Application

• Agrochemical Intermediate: A critical precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the sulfonyl chloride and trifluoromethoxy moieties for enhanced biological activity and stability.
• Pharmaceutical Building Block: Used in medicinal chemistry for the construction of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor modulators.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Dye and Pigment Synthesis: Employed in the production of specialized dyes and pigments where the sulfonyl chloride group facilitates attachment to various matrices.
• Custom Synthesis and Contract Manufacturing: An important reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-Chloro-4-Trifluoromethoxy-Benzenesulfonyl Chloride
CAS No.	748163-14-6
Molecular Formula	C7H3Cl2F3O3S
Molecular Weight	295.07 g/mol
Synonyms	2-Chloro-4-(trifluoromethoxy)benzenesulfonyl chloride; 1-Chloro-2-(trifluoromethoxy)-4-sulfonylchloridebenzene; 4-Chloro-3-(trifluoromethoxy)benzenesulfonyl chloride; Benzenesulfonyl chloride, 2-chloro-4-(trifluoromethoxy)-; 2-Chloro-α,α,α-trifluoro-p-anisylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Trifluoromethoxy-Benzenesulfonyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, NMR, and IR spectroscopy to verify identity and purity. Our quality commitment ensures the material meets the stringent requirements for research and cGMP (current Good Manufacturing Practice) starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.