Description

Benzamide, 3,5-Difluoro-n-(4-Fluorophenyl)- (9Ci) is a high-purity, multi-fluorinated aromatic amide building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific fluorine substitution pattern is crucial for modulating biological activity and physicochemical properties. It is primarily targeted at research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality synthetic intermediates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where fluorine atoms enhance efficacy and environmental stability.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold or labeling agent in the design of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	Benzamide, 3,5-Difluoro-n-(4-Fluorophenyl)- (9Ci)
CAS No.	746612-12-4
Molecular Formula	C13H8F3NO
Molecular Weight	251.21 g/mol
Synonyms	3,5-Difluoro-N-(4-fluorophenyl)benzamide; N-(4-Fluorophenyl)-3,5-difluorobenzamide; 4-Fluoroaniline, N-(3,5-difluorobenzoyl)-; 3,5-Difluoro-N-(4-fluorophenyl)benzamide (9CI); 3,5-Difluoro-N-(4-fluorophenyl)-benzamide; Benzamide, 3,5-difluoro-N-(4-fluorophenyl)-; 746612-12-4
EINECS	Contact for details

Quality Control

Every batch of Benzamide, 3,5-Difluoro-n-(4-Fluorophenyl)- (9Ci) is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable supply for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC, Area %)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.