Description

Aziridine, 1-[(2S)-2,5-Diamino-1-Oxopentyl]- (9Ci) is a specialized chiral aziridine derivative, a high-value building block in advanced organic synthesis. This compound matters for its unique three-membered heterocyclic ring, which provides significant synthetic utility as an electrophilic intermediate for introducing amine functionalities. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, including active pharmaceutical ingredients (APIs) and novel bioactive compounds. CAS No. 743409-13-4.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Peptide Mimetic Research: Used to incorporate constrained, nitrogen-containing ring systems into peptide backbones to modulate biological activity and stability.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides and insecticides with targeted modes of action.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Bioconjugation Chemistry: Utilized for site-specific labeling and cross-linking of biomolecules in biochemical research and diagnostic assay development.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialty polymers with unique chemical or physical properties.

Basic Information

Product Name	Aziridine, 1-[(2S)-2,5-Diamino-1-Oxopentyl]- (9Ci)
CAS No.	743409-13-4
Molecular Formula	C7H13N3O
Molecular Weight	155.20 g/mol
Synonyms	1-[(2S)-2,5-Diamino-1-oxopentyl]aziridine; (2S)-2,5-Diamino-1-(aziridin-1-yl)pentan-1-one; L-Ornithine-derived aziridine; N-(Aziridin-1-ylcarbonyl)-L-ornithine; Aziridine-1-carboxamide, N2,N5-diamino-L-ornithine derivative; Chiral aziridine amide; A building block for constrained peptides
EINECS	Contact for details

Quality Control

Every batch of our Aziridine, 1-[(2S)-2,5-Diamino-1-Oxopentyl]- (9Ci) is produced and tested under strict quality management protocols to ensure identity, purity, and consistency. We provide comprehensive analytical data including chiral purity verification. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), enantiomeric excess, and impurity profiles are available for all shipments. Our quality systems support development from research to commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 95.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.