Description

Ticilimumab Tremelimumab CAS NO 742092-03-1 is a high-purity, biologically active compound classified as a monoclonal antibody. This product is critical for advanced pharmaceutical research and development, particularly in the field of immuno-oncology. It is primarily utilized by biotechnology firms, pharmaceutical manufacturers, and contract research organizations (CROs) engaged in the discovery and production of novel cancer immunotherapies.

Application

• Immuno-oncology Research: Used as a key reagent in preclinical studies to investigate mechanisms of immune checkpoint inhibition.
• Therapeutic Antibody Development: Serves as a reference standard or starting material in the development of CTLA-4 targeting biologics.
• Biopharmaceutical Manufacturing: Employed in process development and optimization for the production of monoclonal antibody-based drugs.
• Cell-Based Assays: Utilized in functional assays to study T-cell activation and modulation of immune responses.
• Diagnostic Development: Acts as a critical component in the development of companion diagnostics for immunotherapy.
• Academic Research: Supports fundamental research in immunology and cancer biology at universities and research institutes.

Basic Information

Product Name	Ticilimumab Tremelimumab
CAS No.	742092-03-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Tremelimumab; Ticilimumab; Anti-CTLA-4 monoclonal antibody; CP-675,206; CP-675206; Immunoglobulin G2, anti-(human cytotoxic T-lymphocyte-associated antigen 4) (human monoclonal CP-675206 γ2-chain), disulfide with human monoclonal CP-675206 κ-chain, dimer
EINECS	Contact for details

Quality Control

Our Ticilimumab Tremelimumab is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including purity assessment by HPLC, identity confirmation, and biological activity assays to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under controlled conditions to prevent degradation. For long-term storage, consider aliquoting and storing at -20°C or below.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Protein Content (UV)	As per COA
Biological Activity (Cell-based assay)	As per COA
Endotoxin (LAL)	< 1.0 EU/mg
Sterility (Membrane Filtration)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.