Description

tert-Butyl 2-Methyl-3-Oxopiperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant importance in modern synthetic chemistry. Its core value lies in serving as a critical building block for the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. This compound is essential for research and development laboratories and production facilities engaged in creating novel active pharmaceutical ingredients (APIs), especially within the fields of central nervous system (CNS) and metabolic disorder therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates and novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used extensively in research and development for structure-activity relationship (SAR) studies and lead optimization.
• Piperidine Derivative Synthesis: Serves as a versatile precursor for the preparation of various substituted piperidine derivatives, a privileged scaffold in drug discovery.
• CNS Drug Development: Particularly relevant in the synthesis of compounds targeting neurological and psychiatric disorders.
• Contract Manufacturing (CMO/CDMO): Supplied to contract manufacturing organizations for cGMP-compliant production of clinical trial materials and commercial APIs.
• Academic & Institutional Research: Utilized in university and institutional labs for methodological development and exploratory synthetic projects.

Basic Information

Product Name	tert-Butyl 2-Methyl-3-Oxopiperidine-1-Carboxylate
CAS No.	741737-30-4
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	1-Boc-2-methyl-3-oxopiperidine; 1-(tert-Butoxycarbonyl)-2-methyl-3-oxopiperidine; tert-Butyl 2-methyl-3-oxo-1-piperidinecarboxylate; 2-Methyl-3-oxo-1-piperidinecarboxylic acid tert-butyl ester; 3-Oxo-2-methylpiperidine-1-carboxylic acid tert-butyl ester; 1-N-Boc-2-methyl-3-piperidone; 2-Methyl-1-Boc-3-piperidone; 741737-30-4
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Methyl-3-Oxopiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring reliable and consistent material for research and cGMP production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥98.0% / ≥99.0% (High Purity Grades Available)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.