Description

2-(Dicyclohexylphosphino)-1-Phenylindole is a specialized organophosphorus ligand with a bulky, electron-rich structure, making it a valuable catalyst component in cross-coupling reactions. Its primary value lies in enhancing reaction selectivity and yield for the synthesis of complex pharmaceutical intermediates and advanced organic materials. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require high-performance ligands for challenging catalytic transformations.

Application

• As a ligand in palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Buchwald-Hartwig amination, and Negishi couplings.
• Catalyst development for the synthesis of active pharmaceutical ingredients (APIs) and key drug intermediates.
• Research and process optimization in academic and industrial laboratories focused on novel organic methodologies.
• Production of specialty chemicals and advanced materials requiring precise molecular construction.
• Use in asymmetric catalysis when combined with appropriate metal centers, due to its sterically demanding architecture.

Basic Information

Product Name	2-(Dicyclohexylphosphino)-1-Phenylindole
CAS No.	740815-36-5
Molecular Formula	C26H32NP
Molecular Weight	389.51 g/mol
Synonyms	1-Phenyl-2-(dicyclohexylphosphino)indole; DCPI; 2-(Dicyclohexylphosphanyl)-1-phenyl-1H-indole; 2-(Dicyclohexylphosphino)-1-phenylindole; 1-Phenyl-2-(dicyclohexylphosphino)indole ligand; Buchwald-type ligand; Bulky phosphine ligand
EINECS	Contact for details

Quality Control

Our 2-(Dicyclohexylphosphino)-1-Phenylindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is characterized by NMR (¹H, ³¹P), HPLC, and elemental analysis to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation, the container should only be opened in an inert environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
³¹P NMR Purity	Conforms
Melting Point	Contact for details
Elemental Analysis	Within theoretical limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.