Description

Benzenepropanenitrile, α-Amino-3-Methoxy-β-Oxo- (9Ci) is a specialized organic nitrile building block featuring a unique amino and oxo functional group arrangement. This compound matters as a versatile chiral intermediate for the synthesis of complex pharmaceutical molecules and advanced agrochemicals. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides and insecticides, where its specific stereochemistry can influence biological activity.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for creating complex, high-value specialty chemicals.
• Academic & Industrial Research: Serves as a valuable substrate in methodological chemistry research, including studies on asymmetric synthesis and catalysis.
• Ligand and Catalyst Development: The amino and nitrile functionalities make it a potential precursor for novel chiral ligands and organocatalysts.

Basic Information

Item	Detail
Product Name	Benzenepropanenitrile, α-Amino-3-Methoxy-β-Oxo- (9Ci)
CAS No.	740035-73-8
Molecular Formula	C11H10N2O2
Molecular Weight	202.21 g/mol
Synonyms	3-Methoxy-2-oxo-3-phenylpropionitrile; 2-Amino-3-methoxy-3-oxo-2-phenylpropanenitrile; α-Amino-β-oxo-3-methoxybenzenepropanenitrile; (Amino)(methoxy)(oxo)phenylpropanenitrile; 740035-73-8; 3-Methoxy-2-oxo-3-phenylpropiononitrile; 2-Oxo-3-methoxy-3-phenylpropionitrile
EINECS	Contact for details

Quality Control

Our Benzenepropanenitrile, α-Amino-3-Methoxy-β-Oxo- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, chiral purity, and impurity profiles are available upon request. We support cGMP standards for advanced intermediate production where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.