Description

4-Methoxy-3-Oxobutanenitrile is a versatile β-ketonitrile building block with a methoxy substituent, offering a reactive handle for constructing complex heterocyclic and pharmaceutical intermediates. Its value lies in its bifunctional nature, enabling diverse synthetic transformations such as cyclizations, condensations, and nucleophilic additions under controlled conditions. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic scaffolds, including pyridines, pyrimidines, and fused ring systems for drug discovery programs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactivity to create targeted bioactive molecules.
• Fine Chemical Production: Serves as a building block for specialty chemicals, dyes, and functional materials requiring specific ketone and nitrile functionalities.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and catalysis studies within R&D laboratories.
• Chemical Library Development: Employed in parallel and combinatorial synthesis to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	4-Methoxy-3-Oxobutanenitrile
CAS No.	739366-02-0
Molecular Formula	C5H7NO2
Molecular Weight	113.11 g/mol
Synonyms	3-Oxo-4-methoxybutanenitrile; 4-Methoxy-3-oxobutyronitrile; 3-Oxobutyronitrile, 4-methoxy-; Butanenitrile, 4-methoxy-3-oxo-; Acetonitrile, (2-methoxy-1-oxoethyl)-; (2-Methoxy-1-oxoethyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 4-Methoxy-3-Oxobutanenitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.