Description

2-Pyrrolidinecarbonitrile,(2R)- is a chiral, non-racemic organic compound belonging to the pyrrolidine class, serving as a valuable synthetic intermediate. Its significance lies in its role as a key building block for the preparation of enantiomerically pure pharmaceuticals and fine chemicals, where stereochemical control is critical. This material is primarily needed by research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce high enantioselectivity.
• Agrochemical Research: Serves as a building block for developing novel, enantiopure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	2-Pyrrolidinecarbonitrile,(2R)-
CAS No.	739363-75-8
Molecular Formula	C5H8N2
Molecular Weight	96.13 g/mol
Synonyms	(R)-2-Cyanopyrrolidine; (2R)-Pyrrolidine-2-carbonitrile; (R)-Pyrrolidine-2-carbonitrile; (R)-2-Pyrrolidinecarbonitrile; (R)-Prolinenitrile; (R)-2-Cyano-pyrrolidine; (R)-1-Azabicyclo[3.3.0]octane-2-carbonitrile (incorrect but sometimes used in searches); (R)-2-Pyrrolidinyl cyanide
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinecarbonitrile,(2R)- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to meet the stringent requirements of advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.