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(11Br)-N,n-Bis[(R)-(-)-1-(2-Methoxyphenyl)Ethyl]Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine CAS NO 736158-72-8


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CAS No.:736158-72-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(11Br)-N,n-Bis[(R)-(-)-1-(2-Methoxyphenyl)Ethyl]Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine is a sophisticated chiral phosphine ligand with a unique dinaphthodioxaphosphepin core structure. This compound is of significant value in asymmetric catalysis, where it acts as a highly effective ligand to control stereoselectivity in critical synthetic transformations. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of enantiomerically pure active pharmaceutical ingredients (APIs) and advanced organic intermediates.

Application

  • As a chiral ligand in asymmetric hydrogenation reactions for the synthesis of enantiomerically enriched compounds.
  • Utilized in asymmetric cross-coupling and carbon-carbon bond-forming reactions in advanced organic synthesis.
  • Critical for pharmaceutical research and development, particularly in creating single-isomer drug candidates.
  • Application in academic research for studying and developing new catalytic methodologies.
  • Potential use in the synthesis of fine chemicals and agrochemicals requiring high stereochemical purity.
  • Serves as a key component in catalyst systems for the production of specialty polymers with controlled tacticity.

Basic Information

Item Details
Product Name (11Br)-N,n-Bis[(R)-(-)-1-(2-Methoxyphenyl)Ethyl]Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine
CAS No. 736158-72-8
Molecular Formula C39H33BrNO3P
Molecular Weight Contact for details
Synonyms (11-Bromo)-N,N-bis[(1R)-1-(2-methoxyphenyl)ethyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine; (R,R)-11-Bromo-4-(bis((R)-1-(2-methoxyphenyl)ethyl)amino)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine; Bromo-SOLPHOS; (R,R)-11-Br-SOLPHOS; Chiral dinaphthodioxaphosphepin ligand; Br-SOLPHOS ligand; Asymmetric phosphine ligand 736158-72-8
EINECS Contact for details

Quality Control

Our (11Br)-N,n-Bis[(R)-(-)-1-(2-Methoxyphenyl)Ethyl]Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for reproducible catalytic performance. All batches undergo rigorous analytical testing, including chiral purity analysis by HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate to maintain stability.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% ee
Loss on Drying ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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