Description

trans-2-[2-(3-Fluorophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid is a high-purity, fluorinated organic intermediate with a defined stereochemistry. This compound is valued for its role as a key building block in the synthesis of complex pharmaceutical molecules and advanced agrochemicals. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used as a building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in route scouting and scale-up processes for the commercial manufacturing of fluorinated active pharmaceutical ingredients (APIs).
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring specific fluorinated motifs and chiral centers.

Basic Information

Product Name	trans-2-[2-(3-Fluorophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid
CAS No.	735274-90-5
Molecular Formula	C15H17FO3
Molecular Weight	264.29 g/mol
Synonyms	2-[(3-Fluorobenzoyl)methyl]cyclohexanecarboxylic acid (trans-); trans-2-[(3-Fluorobenzoyl)methyl]cyclohexanecarboxylic acid; (1R,2R)-2-[2-(3-Fluorophenyl)-2-oxoethyl]cyclohexane-1-carboxylic acid; (1S,2S)-2-[2-(3-Fluorophenyl)-2-oxoethyl]cyclohexane-1-carboxylic acid; 3-Fluoro-ω-oxobenzeneacetic acid trans-2-carboxycyclohexylmethyl ester; 735274-90-5; Fluorinated Cyclohexane Carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our trans-2-[2-(3-Fluorophenyl)-2-Oxoethyl]Cyclohexane-1-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the stringent requirements for pharmaceutical and agrochemical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (trans-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.